Shop. Donate. Volunteer.

Cancer Connection has an award-winning Thrift Shop!

Stop by and see why our thrift shop has been named the best used-clothing store by the Valley Advocate 6 times in the 9 years we have been open!

How to find us

We are located at 375 South Street, Northampton, MA, 01060
Reach us by phone at (413) 587-9999

Please note, we will NOT be accepting any Christmas holiday items during these dates, as we are gratefully stocked with items collected throughout the year.

Shopping Hours:

Wednesday, Thursday, Friday, and Saturday:
10:00 am – 5:00 pm

Sunday, Monday, and Tuesday:
CLOSED

Next Donation Dates

*Please do NOT leave donations outside when we’re closed. Make sure to review our donation guidelines below.

Wednesday, 11/13- Saturday, 11/16

10:00 AM- 2:00 PM

Wednesday, 12/4- Saturday, 12/7

10:00 AM- 2:00 PM

Wednesday, 12/18- Saturday, 12/21

10:00 AM- 2:00 PM

Wednesday, 10/30- Saturday, 11/2

10:00 AM- 2:00 PM

About the Thrift Shop

Founded in 2013, our Cancer Connection Thrift Shop at 375 South Street is in a large, open, sunny space with lots of convenient parking. We offer high-quality, gently used clothing, jewelry, home goods, books, and more at affordable prices.

A knowledgeable, customer-friendly staff led by manager Christine Quinn and a cadre of devoted volunteers will greet you. Stop by and see why our thrift shop has been named the best-used clothing store by the Valley Advocate 6 times.

The Thrift Shop has its own Facebook page — check it out for the latest updates on specials, sales and more.

Volunteer at the Shop

Pink Tags - 50% off, Yellow Tags - 50% off, Green Tags - 50% off, White Tags - 50% off, and Orange Tags - 50% off

Each week get 50% off our featured color tags!

Come on in to see what color is discounted this week.

Frequently asked questions

It’s up to you! Masks are now optional for customers and staff.
Yes! We have three unisex dressing rooms that can be used.
We have a schedule each month that is posted on our website, facebook, and on our outgoing phone message.
We accept cash and credit cards/debit cards.
We take a wide range of items, if they are in saleable condition. We have a handy reference list posted on our Donation Guidelines webpage. We also welcome phone inquiries for out of the ordinary items.

Donation Guidelines

Thank you for your generosity! 100% of our profits go to Cancer Connection and we gratefully accept donations on designated days each month. Please check our donation days listed above.

If you have a large amount of donations, Please call us at 413-587-9999 or email us at thriftshop@cancer-connection.org.

PLEASE never leave donations outside our doors when we are closed! It makes our work much more difficult.

Items that we gratefully accept

We are able to accept donations of men’s, women’s and children’s clothing, vintage clothing, shoes, housewares, jewelry, home decor, antiques, small furniture, art and more. See the full list below:

Gently-Used and New Clothing (Women’s, men’s and children’s)
Vintage Clothing (We love vintage!)
Jewelry (Costume, semiprecious, and precious and watches. We carefully appraise and price.)
Handbags, Purses, and Wallets in good, clean condition.
Accessories (Hats, scarves, belts, gloves, etc…)
Luggage (in good, clean condition)
Gently Worn Shoes, Boots, Sneakers, Sandals…
Art (Paintings, ceramics, photography, etc…)
Antiques
Home Decor (vases, lamps, mirrors, wall hangings, frames, ornaments, etc…)
Pottery
Other Housewares (kitsch, tchotchkes, fine china, platters, etc…)
Kitchenware (dishware, flatware, cookware, small electricals, baking pans, etc…)
Linens (table cloths, curtains, gently used sheets and sheet sets, towels, throws, blankets, etc…)
Rugs, Textiles, Fabrics, Yarn
Books
Ephemera, Memorabilia, Collectibles
Music (CDs and Vinyl)
Musical Instruments
Smaller Furniture (Small chairs, end tables, small book shelves, etc…)

Items that we regretfully cannot accept

We must turn down some of your donations for one or more of the following reasons:

Too heavy, large, costly for us to handle.
Hazardous materials that could create danger in the workplace and would be costly for us to dispose of. We cannot accept donations that would put our volunteers at risk i.e. containing mold, animal droppings or hazardous materials.
Experience tells us we will not be able to sell it in our store.
Existing and new laws have made these items a health and liability risk

Mattresses, Futons & Large Furniture
Large Appliances
Microwaves, Television Sets & electronics
Larger Pieces of Furniture
VHS Tapes
Stereo equipment & camera equipment
Computer Components, Printers, Scanners.
Children’s Toys (Vintage toys, collectibles are OK.)
Wire hangers and plastic hangers
Broken Items and Dirty/Soiled Items
Hazardous materials
Sport & Exercise Equipment, ex. skis, skates, golf clubs, weights etc.
Humidifiers, Air Conditioners &
Electric Heaters
Strollers, Car Seats, Cribs, – Anything that holds an infant.
Food (By law we cannot sell food. Please donate to your local food pantry.)
Large loads of left-over Tag Sale items
Foot baths